Older animation describing the mechanism of action of vancomycin by inhibition of peptidoglycan layer biosynthesis
Mechanism of Action of Penicillin- by inhibition of transpeptidase and preventing the remodeling of the peptidoglycan layer
Mechanism of Action of Penicillin
Michal Addition with a michael acceptor and a michael donor - examples of reactants
Michael Addition
Reaction at the less reactive 6-position of 2-methyl cyclohexanone is forced due to formation of enamine
Producing and Using Imines and Enamines
Screen Shot of the VMD user interface displaying a protein
Visual Molecular Dynamics – VMD
Figure 1: Active site loop of Cdc25 phosphatases with bound sulfate (adapted from PDB ID: 1qb0). The atoms are colored as follows- Carbon: white; Oxygen: red; Nitrogen: blue; Sulfur: yellow; Hydrogen: cyan.
Presentation on – CDC25 Phosphatases: A Potential Target for Novel Anticancer Agents
Figure 1 - Reaction of carbonyl containing compound with amine yields imine and enamine
Imines and Enamines – Nitrogen Analogs of Enols and Enolates
Pharmacogenetics helps in identifying parts of the population based on how they react to a particular drug. In this figure it shows that pharmacogenetics helps in segregating the population according to the rate of metobolism of a particular drug.
Pharmacogenetics Basics
Structure of the nicotinic acetylcholine receptor channel taken from reference 3
Pharmacodynamics Basics
Figure showing the interplay between absorption, distribution, metabolism and excretion (ADME). Taken from reference 3.
Pharmacokinetics Basics- Absorption, Distribution, Metabolism and Excretion
C-alkylation of phenolate
