Class notes taken by students to help study different subjects related to and involving pharmaceutical sciences
Primary Structure of Proteins showing Peptide Backbone
Abstraction of alpha-proton yields a carbanion which is stabilized by enol formation through resonance on either side of malonic ester
Basic conditions force ester hydrolysis and yield carboxylates.
Using the non-selective nature of acetoacetic ester synthesis and malonic ester synthesis to produce cyclic compounds
In the presence of a base alpha-hydrogens to carbonyl functional group can be abstracted very easily to yield a carbanion
Sulfonated Bathophenanthroline, TBTA and Amineriazole
Factor Xa Inhibitors - Rivaroxaban and Apixaban
A plasma-level time curve showing drug absorption and elimination
The gram-molecular weight of a molecule or atom has the same number of molecules or atoms which is equal to Avagadro's Number
C-alkylation vs O-alkylation - A continuous challenge in the chemistry of enolates.
Figure 2 - Energy profile diagram of thermodynamic product vs kinetic product
Examples of drugs include paracetamol and aspirin
A picture showing different drug formulations. Taken from the cover of reference 3.
A picture of a common adverse drug reaction - the skin rash (reference 3)
C-alkylation of phenolate
Figure showing the interplay between absorption, distribution, metabolism and excretion (ADME). Taken from reference 3.