Organic Chemistry Archive
Malonic Ester Synthesis – Alkylation of Enolates
Acetoacetic Ester Synthesis – Alkylation of Enolates
Using the non-selective nature of acetoacetic ester synthesis and malonic ester synthesis to produce cyclic compounds
Chemistry of Enolates and Enols – Acidity of Alpha-Hydrogens
Catalytic Azide-Alkyne Cycloaddition: Reactivity and Application
Chemistry of Enolates – C vs O Alkylation
Thermodynamic Product vs Kinetic Product – with example of enolate formation of 2-methylcyclohexanone
Phenolates- O-alkylation and C-alkylation
Imines and Enamines – Nitrogen Analogs of Enols and Enolates
Producing and Using Imines and Enamines
Michael Addition
Aldol Condensation – Base Catalyzed
Aldol Condensation – Acid Catalyzed
Directed Aldol Synthesis: Part 1 – Formation of E-Enolate and Z-Enolate
Directed Aldol Synthesis: Part 2 – Syn and Anti control using Zimmerman Traxler principle
Boron Enolates for Aldol Synthesis and Other Reactions
Henderson–Hasselbalch Equation: Derivation of pKa and pKb
Thin Layer Chromatography (TLC): Principle (with Animation)
Principle of Reversed-Phase Chromatography HPLC/UPLC (with Animation)
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