Human immunodeficiency virus (HIV) has affected millions of people around the world. The virus is classified as a lentivirus (slowly replicating retrovirus) and is the primary cause of acquired immunodeficiency syndrome (AIDS). The HIV virus causes immune deficiency by targeting the CD4+ T-lymphocytes or helper white blood cells, as well as macrophages and dendritic cells. Over the years, our understanding of the life cycle of the HIV has helped us create several drugs to target this deadly disease.
This is an animation showing the virus life cycle of the HIV virus. A very good animation showing how the HIV virus enters the cell of the body and infects it. It also shows the classes of drugs which can be used or are being used to attack different stages of the virus life cycle. A must see animation for all those who are studying the antiviral drugs either in pharmacology or even medicinal chemistry.
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Pyrido[1,2-a]benzimidazoles has anti HIV-1 activity.