Aldol condensation - leading to aldol or ketol which can undergo dehydration to produce the alpha,beta-unsaturated aldehyde or ketone
Base catalyzed dehydration of aldol or ketol leading to alpha,beta-unsaturated carbonyl compound.
Aldol Condensation – Base Catalyzed
Michal Addition with a michael acceptor and a michael donor - examples of reactants
Michael Addition
C-alkylation of phenolate
Phenolates- O-alkylation and C-alkylation
Figure 2 - Energy profile diagram of thermodynamic product vs kinetic product
Thermodynamic Product vs Kinetic Product – with example of enolate formation of 2-methylcyclohexanone
Basic conditions force ester hydrolysis and yield carboxylates.